Boron,
https://www.ncbi.nlm.nih.gov/pubmed/21129941
"On the first day (day 0), a blood sample collection at 8.00 A.M was followed by ingestion of placebo with the breakfast. On the next day (supplementation-day 1), similar procedure was followed by ingestion of a capsule containing 10mg of boron. On both occasions blood was collected every 2h for the next 6h. Subjects were requested to consume a capsule of 10mg boron every day with their breakfast, and on the day 7, the blood collection was carried out at 8.00 A.M, again.
Boron in plasma increased significantly following hours and weekly consumption. Six hours supplementation showed a significant decrease on sex hormone binding globulin (SHBG), high sensitive CRP (hsCRP) and TNF-α level. After one week (in samples taken at 8.00 A.M, only), the mean plasma
free testosterone increased and the mean plasma estradiol decreased significantly. Dihydrotestosterone, cortisol and vitamin D was elevated. Also, concentrations of
all three inflammatory biomarkers decreased after supplementation"
- free testosterone levels had increased by 28%
- free estrogen levels had decreased by -39%
- dihydrotestosterone (DHT) levels rose by 10%
- many inflammation biomarkers (hsCRP, TNF-α) dropped significantly
https://www.ncbi.nlm.nih.gov/pubmed/3678698
"A boron supplement of 3 mg/day markedly affected several indices of mineral metabolism of seven women consuming a low-magnesium diet and five women consuming a diet adequate in magnesium; the women had consumed a conventional diet supplying about 0.25 mg boron/day for 119 days.
Boron supplementation markedly reduced the urinary excretion of calcium and magnesium; the depression seemed more marked when dietary magnesium was low. Boron supplementation depressed the
urinary excretion of phosphorus by the low-magnesium, but not by the adequate-magnesium, women. Boron supplementation
markedly elevated the serum concentrations of 17 beta-estradiol and testosterone; the elevation seemed more marked when dietary magnesium was low"
https://www.ncbi.nlm.nih.gov/pubmed/7889887
"epidemiologic evidence that in areas of the world where boron intakes usually are 1.0 mg or less/day the estimated incidence of arthritis ranges from
20 to 70%, whereas in areas of the world where boron intakes are usually 3 to 10 mg, the estimated incidence of arthritis ranges from
0 to 10%; d) experimental evidence that rats with induced arthritis benefit from orally or intraperitoneally administered boron; e) experimental evidence from a double-blind placebo-boron supplementation trial with 20 subjects with osteoarthritis.
A significant favorable response to a 6 mg boron/day supplement was obtained; 50% of subjects receiving the supplement improved compared to only 10% receiving the placebo"
https://www.ncbi.nlm.nih.gov/pubmed/16648789
Zinc
,
https://www.ncbi.nlm.nih.gov/pubmed/8875519
"We also measured serum testosterone in nine elderly men (64 +/- 9 y) who were marginally zinc deficient before and after 3 to 6 mo of supplementation with 459 mumol/ d oral zinc administered as zinc gluconate. Serum testosterone concentrations were significantly correlated with cellular zinc concentrations in the cross-sectional study (lymphocyte zinc versus serum testosterone, r = 0.43, p = 0.006; granulocyte zinc versus serum testosterone, r = 0.30, p = 0.03). Dietary zinc restriction in normal young men was associated with a significant decrease in serum testosterone concentrations after 20 weeks of zinc restriction (baseline versus post-zinc restriction mean +/- SD, 39.9 +/- 7.1 versus 10.6 +/- 3.6 nmol/L, respectively; p = 0.005). Zinc supplementation of marginally zinc-deficient normal elderly men for six months resulted in an increase in serum testosterone from 8.3 +/- 6.3 to 16.0 +/- 4.4 nmol/L (p = 0.02). We conclude that zinc may play an important role in modulating serum testosterone levels in normal men"
https://www.ncbi.nlm.nih.gov/pubmed/16648789
"Resting total testosterone and free testosterone levels before zinc supplementation were significantly higher than exhaustion levels before zinc supplementation (p<0.05). Both resting and exhaustion total and free testosterone levels following 4-week zinc supplementation were found significantly higher than the levels (both resting and exhaustion) measured before zinc supplementation (p<0.05)"
Ashwagandha,
https://www.ncbi.nlm.nih.gov/pubmed/26609282
"Compared to the placebo subjects, the group treated with ashwagandha had significantly greater increases in muscle strength on the bench-press exercise (Placebo: 26.4 kg, 95% CI, 19.5, 33.3 vs. Ashwagandha: 46.0 kg, 95% CI 36.6, 55.5; p = 0.001) and the leg-extension exercise (Placebo: 9.8 kg, 95% CI, 7.2,12.3 vs. Ashwagandha: 14.5 kg, 95 % CI, 10.8,18.2; p = 0.04), and significantly greater muscle size increase at the arms (Placebo: 5.3 cm(2), 95% CI, 3.3,7.2 vs. Ashwagandha: 8.6 cm(2), 95% CI, 6.9,10.8; p = 0.01) and chest (Placebo: 1.4 cm, 95% CI, 0.8, 2.0 vs. Ashwagandha: 3.3 cm, 95% CI, 2.6, 4.1; p < 0.001). Compared to the placebo subjects, the subjects receiving ashwagandha also had significantly greater reduction of exercise-induced muscle damage as indicated by the stabilization of serum creatine kinase (Placebo: 1307.5 U/L, 95% CI, 1202.8, 1412.1, vs. Ashwagandha: 1462.6 U/L, 95% CI, 1366.2, 1559.1; p = 0.03), significantly greater increase in testosterone level (Placebo: 18.0 ng/dL, 95% CI, -15.8, 51.8 vs. Ashwagandha: 96.2 ng/dL, 95% CI, 54.7, 137.5; p = 0.004), and a significantly greater decrease in body fat percentage (Placebo: 1.5%, 95% CI, 0.4%, 2.6% vs. Ashwagandha: 3.5%, 95% CI, 2.0%, 4.9%; p = 0.03)"
https://www.ncbi.nlm.nih.gov/pubmed/23439798
"The treatment group that was given the high-concentration full-spectrum Ashwagandha root extract exhibited a significant reduction (P<0.0001) in scores on all the stress-assessment scales on Day 60, relative to the placebo group. The serum cortisol levels were substantially reduced (P=0.0006) in the Ashwagandha group, relative to the placebo group".
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270108/
"Sixty-two abstracts were screened; five human trials met inclusion criteria. Three studies compared several dosage levels of WS extract with placebos using versions of the Hamilton Anxiety Scale, with two demonstrating significant benefit of WS versus placebo, and the third demonstrating beneficial effects that approached but did not achieve significance (p=0.05). A fourth study compared naturopathic care with WS versus psychotherapy by using Beck Anxiety Inventory (BAI) scores as an outcome; BAI scores decreased by 56.5% in the WS group and decreased 30.5% for psychotherapy (p<0.0001). A fifth study measured changes in Perceived Stress Scale (PSS) scores in WS group versus placebo; there was a 44.0% reduction in PSS scores in the WS group and a 5.5% reduction in the placebo group (p<0.0001)"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545242/
There was significant improvement in the experimental group in all parameters, whereas the placebo group did not show any change with respect to their baseline parameters. There was significant improvement in the experimental group in all parameters, namely, VO2 max (t = 5.356; P < 0.001), METS (t = 4.483; P < 0.001), and time for exhaustion on treadmill (t = 4.813; P < 0.001) in comparison to the placebo group which did not show any change with respect to their baseline parameters.
Resveratrol,
"When the Chinese exposed SK-BR-3 cells to resveratrol they saw that the higher the concentration of resveratrol, the less active the aromatase became. The first figure below shows this. The second figure below shows how resveratrol reduced the aromatase production in the same cell type"
If you say 'anti-oestrogen' to strength athletes, they automatically think 'more testosterone'. This association is correct, if resveratrol is the substance in question, according to an animal study done at the Universitat de Barcelona, which is where we found the figure shown above. [J Nutr. 2005 Apr; 135(4): 757-60.]
It shows what happens to testosterone and sperm production if you give mice 20 mg resveratrol per kg bodyweight for 90 days in a row. A conservative estimate of the equivalent dose for humans is 2 mg per kg bodyweight.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC28446/
"Furthermore, it activates the expression of estrogen-responsive reporter genes in several different human cell lines, and this activation is inhibited by estrogen antagonists. Resveratrol also fully activates expression of endogenous estrogen-regulated genes, and it induces the proliferation of T47D breast cancer cells"
Ме мрзеше за сите да барам студии, мислам дека добро ви се познати магнезиум и D3, се фокисурав на помалце познатите суплементи. Лично искуство имам, како и доста мои пријатели, сите имаат одлични резултати во повеќето парамтери на квалитет на живот, перформанси при вежбање, мускулна маса, распложение, мотивација, ведрина, смиреност, анти анксиозно и анти депресивно дејство, самодоверба. Еден дечко од форумов, го зголеми тестостеронот од некои 200 на 780, и тоа само од борон, цинк и магнезиум, и неколку билки (турмерик, ѓумбир и црно семе)
Кај него беше низок од старт, но да дојдеш до 780 со дијабет, е неверојатна бројка - знаејќи дека не зима никакви хемии, исто така LDL падна од 3.9 на 2 тоталниот холестерол падна од 5.2 на 4 а HDL се зголеми од 1 на 2 - се ова за само 1-2 месеци, да постигнеш 1:1 холестерол, а да имаш дијабет е скоро невидено, и самите доктори кога иде на прегледи (крвна слика) се чудат и го прашуваат што прави и како е тоа можно
ама, кој ќе заслужи, добива. 