A
anaveno
Гостин
Y-chromosome and mtDNA polymorphisms in Iraq,..
A Crossroad of the Early Human Dispersal and of Post-Neolithic Migrations
N. Al-Zahery,a,b O. Semino,a G. Benuzzi,a C. Magri,a G. Passarino,c
A. Torroni,a and A.S. Santachiara-Benerecettia,*
a Dipartimento di Genetica e Microbiologia ‘‘A. Buzzati Traverso’’, Universita di Pavia, Via Ferrata, 1, 27100 Pavia, Italy
b Department of Biotechnology, College of Science, University of Baghdad, Baghdad, Iraq
c Dipartimento di Biologia Cellulare, Universita della Calabria, Cosenza, Italy
Received 29 May 2002; revised 11 December 2002
Abstract
Analyses of mtDNA and Y-chromosome variation were performed in a sample of Iraqis, a scarcely investigated population of
the ‘‘Fertile Crescent.’’ A total of 216 mtDNAs were screened for the diagnostic RFLP markers of the main Eurasian and African
haplogroups. A subset of these samples, whose HVS-I sequences were previously obtained, was also examined by high-resolution
restriction analysis. The Y-chromosome variation was investigated in 139 subjects by using 17 biallelic markers and the 49a,f/Taq I
system. For both uniparental systems, the large majority of the haplogroups observed in the Iraqi population are those (H, J, T,
and U for the mtDNA, and J(xM172) and J-M172 for the Y chromosome) considered to have originated in the Middle East and
to have later spread all over Western Eurasia. However, about 9% of the mtDNAs and 30% of the Y-chromosomes most likely
represent arrivals from distant geographic regions. The different proportion of long-range genetic input observed for the mtDNA
and the Y chromosome appears to indicate that events of gene flow to this area might have involved mainly males rather than
females.
2003 Published by Elsevier Science (USA)
and the Greek as well as ancient contacts with Ethiopia
(Malaspina et al., 2001; Mitchell and Hammer, 1996;
Passarino et al., 1998; Santachiara-Benerecetti and Semino,
1996; Scozzari et al., 2001).
P.S. превентива, ако на некој му текне да спомне Грци...
A Crossroad of the Early Human Dispersal and of Post-Neolithic Migrations
N. Al-Zahery,a,b O. Semino,a G. Benuzzi,a C. Magri,a G. Passarino,c
A. Torroni,a and A.S. Santachiara-Benerecettia,*
a Dipartimento di Genetica e Microbiologia ‘‘A. Buzzati Traverso’’, Universita di Pavia, Via Ferrata, 1, 27100 Pavia, Italy
b Department of Biotechnology, College of Science, University of Baghdad, Baghdad, Iraq
c Dipartimento di Biologia Cellulare, Universita della Calabria, Cosenza, Italy
Received 29 May 2002; revised 11 December 2002
Abstract
Analyses of mtDNA and Y-chromosome variation were performed in a sample of Iraqis, a scarcely investigated population of
the ‘‘Fertile Crescent.’’ A total of 216 mtDNAs were screened for the diagnostic RFLP markers of the main Eurasian and African
haplogroups. A subset of these samples, whose HVS-I sequences were previously obtained, was also examined by high-resolution
restriction analysis. The Y-chromosome variation was investigated in 139 subjects by using 17 biallelic markers and the 49a,f/Taq I
system. For both uniparental systems, the large majority of the haplogroups observed in the Iraqi population are those (H, J, T,
and U for the mtDNA, and J(xM172) and J-M172 for the Y chromosome) considered to have originated in the Middle East and
to have later spread all over Western Eurasia. However, about 9% of the mtDNAs and 30% of the Y-chromosomes most likely
represent arrivals from distant geographic regions. The different proportion of long-range genetic input observed for the mtDNA
and the Y chromosome appears to indicate that events of gene flow to this area might have involved mainly males rather than
females.
2003 Published by Elsevier Science (USA)
and the Greek as well as ancient contacts with Ethiopia
(Malaspina et al., 2001; Mitchell and Hammer, 1996;
Passarino et al., 1998; Santachiara-Benerecetti and Semino,
1996; Scozzari et al., 2001).
P.S. превентива, ако на некој му текне да спомне Грци...
