- Член од
- 1 ноември 2010
- Мислења
- 595
- Поени од реакции
- 241
Археогенетика-пример
The Archaeogenetics Group studies the geographic distribution of modern human genetic variation, with the aim of addressing questions from archaeology, anthropology and history.
http://www.hud.ac.uk/research/researchcentres/targ/
Историска геномика
The population genetic relationships have been compared with the history of the classical populations living in the area. A revision of the historic postulates would have to be undertaken, particularly in the cases when genetics and history are overtly discordant.
DNA sequencing and polymorphism have widely been used to study ethnic groups in order to outline population history and to detect their possible migrations and interactions with neighbours over time.
Since history is a largely subjective area in terms of our present knowledge, highly polymorphic DNA variants are often able (although not always) to define populations or ethnic groups and thus allow inferences about their historical-prehistorical interactions: this subject I call historic genomics. The existence or absence of gene flow among neighboring ethnic groups may be assessed with the study of HLA frequencies and the corresponding genetic distances (1, 2).
When historical characteristics are present, HLA is able to detect them: for example, the A29-B44 haplotype is frequent in northern Spaniards (including Basques), Irish, southern British and western French (7). Thus, this marker relates all these groups and their history (or prehistory) must have common genetic grounds.
Other molecular markers, like mtDNA and Y Chr are widely used for this type of research. They are also subject to selection since they are linked to diseases (OMIM: On line Mendelian Inheritance in Man), as are a number of HLA alleles.
(извор: Villena 2002-Population genetic relationships between Mediterranean populations)
P.S.
Се надевам дека администраторите ќе придонесат за подобрување на квалитетот на форумот, и дека (барем) на вакви теми ќе се задржи дигнитетот.
.
The Archaeogenetics Group studies the geographic distribution of modern human genetic variation, with the aim of addressing questions from archaeology, anthropology and history.
http://www.hud.ac.uk/research/researchcentres/targ/
Историска геномика
The population genetic relationships have been compared with the history of the classical populations living in the area. A revision of the historic postulates would have to be undertaken, particularly in the cases when genetics and history are overtly discordant.
DNA sequencing and polymorphism have widely been used to study ethnic groups in order to outline population history and to detect their possible migrations and interactions with neighbours over time.
Since history is a largely subjective area in terms of our present knowledge, highly polymorphic DNA variants are often able (although not always) to define populations or ethnic groups and thus allow inferences about their historical-prehistorical interactions: this subject I call historic genomics. The existence or absence of gene flow among neighboring ethnic groups may be assessed with the study of HLA frequencies and the corresponding genetic distances (1, 2).
When historical characteristics are present, HLA is able to detect them: for example, the A29-B44 haplotype is frequent in northern Spaniards (including Basques), Irish, southern British and western French (7). Thus, this marker relates all these groups and their history (or prehistory) must have common genetic grounds.
Other molecular markers, like mtDNA and Y Chr are widely used for this type of research. They are also subject to selection since they are linked to diseases (OMIM: On line Mendelian Inheritance in Man), as are a number of HLA alleles.
(извор: Villena 2002-Population genetic relationships between Mediterranean populations)
P.S.
Се надевам дека администраторите ќе придонесат за подобрување на квалитетот на форумот, и дека (барем) на вакви теми ќе се задржи дигнитетот.
.