Читам мите јан планираш да користиш миниксидил, што со финастерид?
Го читнав малку хер лос форумот и еве што открив откриле нов ДХТ блокатор што демек нема контраефекти, а е 2 пати посилен од финастеридот (генеричко име за пропециа)
CB-03-01 Is a new topical antiandrogen, you can see the abstract from the CB-03-01 study here-
извор:
http://www.hairlosstalk.com/interact/viewtopic.php?f=11&t=63313
Американциве си се договараат на форум да си го порачаат од некоја си кинеска лабораторија, го дистрибуирале во вид на прашок, добро за нив кај нас неможеш да најдеш квалитетен миноксидил не па овакво нешто, мене лично иначе не ми опаѓа косата но сакам да си го зајакнам влакното па затоа се заинтересирав за проблематикава..
''The aim of this study was to investigate the antiandrogenic activity of a new monoester of cortexolone, cortexolone 17alpha-propionate (CAS 19608-29-8, CB-03-01). Although the compound displayed a strong local antiandrogenic activity in hamster's flank organ test, it did not exhibit antiandrogenic activity in rats after subcutaneous injection, nor did it affect gonadotropins hypersecretion when injected to parabiotic rats. As topical antiandrogen, the steroid resulted about 4 times more active than progesterone (CAS 57-83-0) and, when compared to known antiandrogen standards, it was about 3 times more potent than flutamide (CAS 13311-84-7), about 2 times more effective than finasteride (CAS 98319-26-7) and approximately as active as cyproterone acetate (CAS 427-51-0). Its pharmacological activity seemed to be primarily related to its ability to antagonistically compete at androgen receptor level; nevertheless its primary pharmacological target needs to be further investigated. Its topical activity, along with the apparent absence of systemic effects, anticipates this compound to have the potential of representing a novel and safe therapeutic approach for androgen-dependent skin disorders.